John Kolega, M.Phil., Ph.D.

Dr. Kolega's primary research interest is the behavior of endothelial cells, which form the inner lining of blood vessels and are key players in the remodeling events that occur during wound healing, aneurysm formation, tumor growth, and a wide variety of disease conditions. In his own lab, they look at how endothelial cells sense and respond to their mechanical environment.

Here at the TSRC, Dr. Kolega mentors students in the use of cell culture and whole animal systems to examine how endothelial cells respond to specific hemodynamic micro-environments in order to understand the mechanism and regulation of flow-induced remodeling, especially as it relates to cerebral aneurysms.

Selected Publications